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LogoName Σ Employees
OSE Immunotherapeutics OSE Immunotherapeutics

Immuno-Oncology and Immuno-Inflammation - Breakthrough Immuno-Science for Patients OSE Immunotherapeutics is an integrated biotech company focused on developing first-in-class assets targeting cancer and inflammatory diseases. A current well-balanced first-in-class clinical pipeline including: • Tedopi® (T-cell specific immunotherapy): Company’s most advanced product; positive results for Ph 3 in NSCLC in secondary resistance after CKI failure. Other sponsored combo Ph 2 trials in solid tumors ongoing. • OSE-279 (anti-PD1) advanced preclinical stage • OSE-127 (humanized mAb antagonist of IL-7R); ongoing Ph 2 in Ulcerative Colitis; ongoing preclinical research in leukemia • VEL-101/FR104 (anti-CD28 mAb) developed in partnership with Veloxis in transplantation; ongoing …

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

16 9 6 74
REGEnLIFE REGEnLIFE

Neurotech & photomedicine REGEnLIFE is an innovative company developing cutting-edge therapy for neurodegenerative disorders. Our company supports a non-invasive medical approach based on physical sciences. Our mission is to develop innovative and responsible technologies to face up to medical challenges and public health needs. Our goal is to provide to healthcare professionals a technology able to alter the progression of neurodegenerative diseases, in order to improve the health and quality of life to promote a healthy aging process. Our technology consists in a novel medical device dedicated to people living with neurodegenerative diseases, specifically Alzheimer-type dementia. MedTech, NeuroTech, Neurophonic, Photonics, …

Type: Startup Activities: biotech deeptech healthtech manufacturing Technologies: Synthetic Biology

22 3 12 12
Cellenion Cellenion

Experts in single cell isolation technology for sequencing and cell line development applications. Cellenion offers solutions and technologies for controlled cell dispensing with applications in the fields of single-cell isolation and bioprinting : Ability to manipulate single-cell has long been a challenge for the scientific community due to their micrometric size and delicate nature. Cellenion has developed and patented CellenONE, a breakthrough single cell isolation and dispensing technology. CellenONE provides outstanding single cell precision, high throughput, and unmatched recovery. Bioprinting is the process of generating spatially-controlled cell patterns using 3D printing technologies. Cellenion will aim toward both miniaturization and automation …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

3 1 2 25
NeoVirTech NeoVirTech

Virus and viral vector imaging in living cells applied to antiviral discovery and disinfection processes NeoVirTech (NVT) is one of the leading virus imaging and antiviral discovery company in Europe. The company has been highlighted in the Top10 drug discovery companies, Europe, 2019 by the PharmaTechOutlook Magazine. NVT has developed a breakthrough technology to directly visualize and quantify in real time virus/viral vector infection and replication in living cells, from high resolution to high content imaging. At NeoVirTech, we believe everyone can have access to state-of-the-art virology techniques. We are focusing our activities on antiviral discovery, study of oncolytic and …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

13 2 6 6
Valerio Therapeutics Valerio Therapeutics

Valerio is a clinical-stage biotechnology company developing novel oncology drugs targeting tumor DNA-binding functions. Valerio Therapeutics is a clinical-stage biotechnology company based in France and the US that develops new drugs by targeting tumor DNA functions through unique mechanisms of action in the field of DNA Damage Response (DDR). DDR consists of a network of cellular pathways that detect, report and repair DNA damage. Applied to oncology, this new field of research aims to weaken or block the ability of tumor cells to repair damage to their DNA, either naturally or under the effect of cytotoxic treatments. Focusing exclusively on …

Type: Startup Activities: biotech deeptech manufacturing Technologies: Synthetic Biology

1 1 0 64
IMACTIV-3D IMACTIV-3D

Unlock the full potential of your preclinical studies with 3D imaging, image processing and our biological models Imactiv-3D mission is to assess the efficacy of a molecule of interest by using innovative imaging and quantification tools, and by implementing powerful image processing algorithms on relevant 3D models. Imactiv-3D is a fee-for-services company born from the meeting between biology, imaging and image processing experts. By working together, we have developed 3D imaging procedures to explore biological samples and image analysis algorithms to automatize and strengthen characterization and quantification on innovative 3D models. This complementary expertise along with our R&D service allow …

Type: Startup Activities: deeptech biotech Technologies: A.I. A.I. - Image Processing Data Analytics A.I. - Machine Learning

2 0 2 7
Roca Therapeutics Roca Therapeutics

A united team creating an innovative therapy to give a new life / vision to patients First In Class Drugs against diseases favored by hyper-vascularization and immuno-suppressive inflammation Cancer treatment, Eye disease, Angiogenesis, Inflammation, Drug development, and Personalized therapy

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

11 4 5 6
Aenitis Technologies Aenitis Technologies

Acoustic Cell Processing Solution 🚀 Aenitis designs, develops, and markets sole-in-class acoustofluidic technology that makes cell and gene therapy manufacturing better, safer, and less expensive. By precisely controlling levitated cells with sound waves, our systems handle cells in full sterile conditions and radically increase productivity while preserving the native state of cells at every step of the engineering process. This technology enables gentle, non-invasive manipulation of cells at the millifluidic scale, allowing for the handling of tens of milliliters per minute. Such capabilities are critical for scaling applications from research to clinical and industrial use. 💡Today, we have achieved proof-of-concepts …

Type: Startup Activities: deeptech healthtech biotech Technologies: Synthetic Biology

21 5 17 17
EVerZom EVerZom

Revolutionizing healthcare with exosomes focusing on gastrointestinal, liver and kidney regeneration EverZom is an exosome biotech company developing treatments for digestive tissue healing like Crohn's fistula and organ regeneration like the kidney and the liver. Founded in 2019, EverZom is positioned to become the leader of exosome therapeutics, the next wave of innovation for the biotech industry. Exosomes, small vesicles secreted by cells, are increasingly recognized as potent agents for intercellular communication and play a crucial role to treat a wide range of diseases. Winner of the European EIC Accelerator Program, EVerZom aims to be the upcoming pioneer in this …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

13 13 0 15
Corlieve Therapeutics Corlieve Therapeutics

At Corlieve, we are focused on bringing novel therapeutic options to patients with severe neurological disorders. Corlieve Therapeutics, a fully owned subsidiary of UniQure, is a biotechnology company focused on bringing novel therapeutic options to patients with severe neurological disorders.

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

2 2 0 2
PHARNEXT PHARNEXT

New therapies for neurodegenerative diseases Pharnext is an advanced clinical-stage biopharmaceutical company developing novel therapeutics for neurodegenerative diseases that currently lack curative and/or disease-modifying treatments. Pharnext has two lead products in clinical development. PXT3003 completed an international Phase III trial with positive topline results for the treatment of Charcot-Marie-Tooth disease type 1A (‘CMT1A’) and benefits from orphan drug status in Europe and the United States. An international pivotal Phase III study of PXT3003 in CMT1A, the PREMIER trial, is currently ongoing. PXT864 has generated encouraging Phase II results in Alzheimer’s disease and will be advanced through partnerships. Both of Pharnext’s …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

5 4 2 23
SYNSIGHT SYNSIGHT

Synsight activity is now integrated into @iktos https://iktos.ai/ https://www.linkedin.com/company/iktos/ Synsight is a company created in 2013, and is now integrated in @iktos company. Its tech is based on AI drug design and cell imaging, including a proprietary cell based assay named MTBench, to profile compounds modulators of protein-protein and protein-RNA interactions, and protein agregation. criblage virtuel, modélisation moléculaire, dynamique moléculaire, QSAR, drug design, chémoinformatique, and drug discovery

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

12 2 9 2
AUROBAC THERAPEUTICS AUROBAC THERAPEUTICS

Developing precision medicines to combat bacterial infections, AMR, and their consequences in acute care settings. AUROBAC THERAPEUTICS is a biopharmaceutical company founded in 2022 by three highly renowned life sciences innovation companies, Boehringer Ingelheim, Evotec and bioMérieux, to develop the next generation of precision medicines to combat bacterial infections, Antimicrobial Resistance (AMR), and their consequences in acute care settings. AUROBAC’s R&D strategy addresses these unmet medical needs with patient- and pathogen-targeted programs designed to tackle both the causes and consequences of potentially life-threatening bacterial infections and AMR, including hospital-acquired and ventilator-associated bacterial pneumonia (HABP and VABP) and sepsis. Central to …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

4 1 3 23
RebrAIn RebrAIn

ReBrain standardizes targeting for DBS and brain lesion surgeries in Parkinson and essential tremor diseases RebrAIn offers a precise targeting technology for Deep Brain Stimulation (DBS). This is achieved through an algorithm based on Artificial Intelligence and a collaborative health data registry. With this innovative technology, developed to effectively identify the areas of the brain to be treated, ReBrain simplifies and standardizes DBS by reducing the risks and making it less traumatic, thus allowing more patients worldwide to be treated.

Type: Startup Activities: deeptech healthtech biotech Technologies: A.I. Data Analytics

17 7 8 18
LXRepair 2013-2023 LXRepair 2013-2023

2013-2023 In a context where the rate of cancer treatment failure is still unacceptably high, our mission is to provide decision aids to oncologists. We believe that profiling is key to predicting treatment toxicity to patients and effectiveness on tumors. Over a decade of research by the French Atomic Energy Commission (CEA) on the impact of radiations on DNA has resulted in a deep understanding of the essential DNA repair mechanisms. More recently, a set of innovative biomarkers was developed that provides a complete functional signature of these mechanisms, the premise to powerful tools for personalized treatment of cancer. http://www.lxrepair.com …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

3 1 2 3
NETRI NETRI

INNERVATE. SCREEN. PREDICT. NETRI is a technology enabling company that provides human cell based smart assays for high throughput preclinical data acquisition for the neurological Pharma & Cosmetics industries. We provide organs-on-chip solutions & interoperable in vitro models designed to deeply accelerate drug discovery and preclinical trials by mimicking in vivo neural connectivity. neuroscience, microfluidics, neural network, organ on chip, neurofluidics, neurological troubles, Alzheimer, Parkinson, organonchip, dermo-cosmetics, and toxicology

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

30 10 25 38
Osivax Osivax

Pioneering A New Class of Universal Vaccines Osivax is a clinical-stage biopharmaceutical company leveraging its novel, self-assembling nanoparticle platform technology, oligoDOM, to develop transformative, first-in-class pan-respiratory virus vaccines generating superior T-cell responses in addition to strong and sustained B-cell responses. The company is establishing proof of concept with its broad-spectrum, “universal” influenza candidate, OVX836, which is currently in Phase 2 clinical trials with over 1200 subjects tested and encouraging efficacy proof of concept data. Osivax’ ambition is to develop a pan-respiratory virus vaccine to prevent all strains of influenza and all variants of sarbecovirus in one single shot. The company …

Tags: FrenchTech2030 Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

23 11 15 52
Da Volterra Da Volterra

Clinical stage biotechnology company whose vision is to be a trusted and acknowledged leader in the microbiome field. Da Volterra is a clinical stage biotechnology company whose vision is to be a trusted and acknowledged leader in the microbiota field. Our mission is to discover, develop and bring to market safe and novel therapeutic options, preserving patients’ microbiota to prevent and cure life-threatening diseases. We strive to serve patients by transforming the promise of science into innovative treatments which have the power to improve health and save lives.​ Committed to innovation, Da Volterra develops products intended to protect the intestinal …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

5 2 2 7
Qynapse Qynapse

The future of neuroimaging is here. Qynapse offers groundbreaking peace of mind by providing results you can trust. The future of neuroimaging analysis is here and Qynapse is leading the way. For clinicians on the front lines, for patients and their families, for payers, and for pharma – we offer peace of mind by providing results you can trust. Headquartered in France, in the United States and in Canada, the Qynapse team, with our world-renowned team of scientific and clinical partners, is wholly dedicated to aspiring to bring the entire neuroscience community and their patients the clearest, most accurate and …

Type: Startup Activities: healthtech biotech deeptech it services Technologies: Affective Computing A.I. A.I. - Machine Learning

13 5 8 23
Enalees Enalees

Easy & Fast Enalees is a biotech specialized in the development and marketing of lyophilized molecular diagnostic tests for animal healthcare in Europe. Leader of PCR type veterinary tests, Enalees uses the technology named LAMP (Loop-mediated isothermal amplification) to diagnose infectious canine, feline, and equine diseases in a simple, rapid, and reliable fashion. Thanks to its expertise in lyophilization, Enalees also provides development opportunities for other companies in the health, agriculture, and environment sector. Relocating the creation and production of rapid molecular diagnostic tests in France has also become an ambition of the company. Enalees already demonstrated the proof of …

Type: Startup Activities: pettech biotech

18 5 6 34
ONCOMECA ONCOMECA

Early diagnosis of skin cancers has never been that easy! ONCOMECA is a class IIb medical device according to the EU regulation 2017/745. Our technology lies in the identification of early skin cancers using their mechanical markers combined to their visual characteristics. Our expertise has been miniaturized and automatized to provide an easy-to-use and 90% reliable technology!

Type: Startup Activities: deeptech biotech healthtech Technologies: Synthetic Biology

0 0 0 1
BIOMUNEX PHARMACEUTICALS BIOMUNEX PHARMACEUTICALS

BIOMUNEX is a biopharmaceutical company focused on the discovery and development of breakthrough immunotherapeutics BIOMUNEX Pharmaceuticals is a biopharmaceutical company focused on the discovery and development of breakthrough immunotherapies using its Unique BiXAb® technology to create next generation bi- and multi-specific antibodies. Our disruptive biological approaches target a number of cancer types, in particular where there are unmet medical needs. We are committed to provide oncologists and patients with immunotherapies that are novel, efficacious and prolong life expectancy.

Type: Startup Activities: deeptech biotech

4 3 1 12
IMODI Cancer IMODI Cancer

Building a sustainable sector and accelerate the discovery of new treatments tailored to each patient. French consortium to develop new experimental models of cancer in 9 cancer pathologies of interest (Lung, Pancreas, Breast, Liver, Ovary...) 3 major R&D axes: - Developing in vivo models and cell-based assays - Mimicking the human biology by humanizing the tumor microenvironment in mice - Studying the microbiota in cancer patients Oncology, Cancer research, Patient derived Xenograft, Cell lines, Ex vivo assays, Microbiota, Data mining , Translationnal medecine, Humanized mice, Biomarker, Research and Development, In vivo models, Ex vivo models, and Cancer

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

1 0 0 N/A
ECONICK ECONICK

[Automatic translation follows] Plant biotechnology company producing eco-responsible metals from plants Bio-sourced strategic metals supplier & Phytoremediation services Econick, a startup founded by researchers from laboratories in the Grand Est region, has developed an innovative process exploiting the potential of so-called hyperaccumulator plants to extract certain metals from contaminated or naturally mineralized soils.

Type: Startup Activities: greentech biotech deeptech Technologies: Bio sourced materials

1 1 0 8
Diamidex Diamidex

Make Visible the Invisible Faster to Make your World Safer Founded in 2014, DIAMIDEX (Diagnostic Microbiology Express) is an innovative company specialized in the detection and quantification of microorganisms of interest. Its mission: making the invisible visible faster, to make your world safer. Its patented innovative technological approach brings about a major breakthrough to meet the speed and technicality challenges arising from microbiological culture. Based on a powerful technological platform, recognized by the scientific and industrial communities, DIAMIDEX offers and develops turnkey test solutions, which can be used in both laboratories and in the field to obtain a quantitative count …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

14 7 9 27
Lynxter SAS Lynxter SAS

Lynxter is an additive manufacturing machine tools manufacturer, open and industry 4.0 oriented. Lynxter is an additive manufacturing machine tools manufacturer, open and industry 4.0 oriented. A French start-up born in a garage under the sun of the Pays Basque (Bayonne), offering industry 4.0 open additive manufacturing machine-tools to industries (aerospace, biomedical, etc.), education and communities (technological platforms and fablabs). #versatility #performance #safety #productivity #reliability #specific We believe in creators. We are the right hand of demanding people who create and develop, by providing the best tools to materialise their ideas (rapid prototyping) and bring these ones to the market …

Type: Startup Activities: biotech deeptech edtech industry 4.0 manufacturing Technologies: 3D Printing

24 11 16 27
BIODOL THERAPEUTICS BIODOL THERAPEUTICS

An Innovative Treatment for Chronic Pain BIODOL Therapeutics is a biotech company developing first-in-class compounds for treating chronic pain. It is based on the discovery by Biodol's scientists of the target FLT3, which is a master hub protein in the initiation and maintenance of neuropathic pain (Nature Communications 2018). Morevover, Biodol discovered that its FLT3 breakthrough platform will also help fighting the "Opioid Crisis"​ (patented but yet unpublished). Biodol has a series of FLT3 selective small-molecule extracellular antagonists. The Biodol's FLT3 technological Platform is worldwide protected by 5 patents.

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

5 4 0 7
Inoviem Scientific Inoviem Scientific

Creative Technologies for Efficient Therapeutics, Precision medicine Inoviem Scientific is a private Bioanalytical company which delivers enabling information to secure drug discovery programs and to take informed decision by closing the gap between preclinical and clinical development. We reconcile translational pharmacology and human physiology by using fresh patient material from the target cohort, embracing the complexity of human diseases. Inoviem's enabling technologies are working in pathological conditions to get the treatment in development to the right patient. Our indication-agnostic access to patients combined with innovative label-free platforms deliver Target identification and validation, targets & Mode of Action deconvolution, patient stratification, …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

0 0 0 11
ViroScan3D ViroScan3D

Solutions Personnalisées de Génomique ViroScan3D is a service provider in genomic and micro-genomic located in Lyon. We have ten year experience in genome scale analyses from sample preparation to data analysis. During those years we have developed specific processes dedicated to complex samples (low quality and quantity samples). We propose our services for -Molecular broad spectrum identification of infectious agents, new agents, resistance mutants by whole genome sequencing of viruses and microorganisms (bacteria, yeast, fungi, etc.) -Analysis of complex populations using the metagenome, virome, bacteriome approach to identify the different agents in the population and their proportions -The identification of …

Type: Startup Activities: deeptech biotech Technologies: Data Analytics Synthetic Biology

0 0 0 2
Valneva Valneva

Specialty vaccine company focused on prevention of infectious diseases with major unmet need, such as Lyme & chikungunya Valneva is a specialty vaccine company that develops, manufactures, and commercializes prophylactic vaccines for infectious diseases addressing unmet medical needs. We take a highly specialized and targeted approach, applying our deep expertise across multiple vaccine modalities, focused on providing either first-, best- or only-in-class vaccine solutions. We have a strong track record, having advanced multiple vaccines from early R&D to approvals, and currently market three proprietary travel vaccines, including the world’s first and only chikungunya vaccine, as well as certain third-party vaccines. …

Type: Startup Activities: biotech healthtech manufacturing Technologies: Synthetic Biology

24 11 6 654
Dendris Dendris

[Automatic translation follows] Molecular Diagnosis Dendris is a start-up exploiting an innovative technology for the design of biochips. The Dendris technology is based on a patented surface chemistry from dendrimers and on a syndromic approach from a multiplex PCR. The data analysis is carried out using dedicated software based on a statistical learning method constantly enriched by new data. This device allows to obtain a rapid diagnosis for medical, environmental and food applications. molecular biology, in vitro diagnostics, Artificial Intelligence, and Dendrimers

Type: Startup Activities: deeptech biotech Technologies: Data Analytics

1 1 0 7
DIAG2TEC DIAG2TEC

Preclinical CRO in Hematological Cancers Diag2Tec is an expert preclinical CRO devoted to hematological cancers, especially Multiple Myeloma (MM). We focused on in vitro Drug Testing in Human Hematological Cancer derived Cell Lines and Primary Cells from patients with various Hematologic Malignancies (Multiple Myeloma, Diffuse Large B Cells Lymphoma (DLBCL), Acute Myeloid Leukemia (AML), Mantle cell Lymphoma, Chronic Lymphoid Leukemia...). With our 2 platforms : Drug Testing Services and ChimioFx, our mission is to provide efficient treatment solutions for patients suffering from Hematological Malignancies with Precision Medicine approaches. We support biotech and phamaceutical companies to focus their drug development on …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

2 2 0 8
Doklog Doklog

[Automatic translation follows] Create your health communication platform Your health information network. Platform intended for all health stakeholders: professionals, patients, establishments, associations, authorities, manufacturers, etc.). health, social media, hcsmeufr, and startup

Type: Media Startup Activities: healthtech biotech deeptech Technologies: SaaS

1 0 0 0
GLOKIS GLOKIS

[Automatic translation follows] Supporting territories on sustainable circular and low-tech solutions Restoring and preserving the marine environment Reservation, Diving, Booking, Scuba Diving, science, biology, and ocean protection

Type: Startup Activities: biotech deeptech it services Technologies: Decarbonization

5 2 1 3
Alvéole Alvéole

Bioengineering unleashed! Tools for better cell sample preparation: better cell models for cell biology and microscopy. Created from work carried out by three research experts, Alvéole’s goal is to make the control of living cells the future of cell biology. A company specialized in devices for controlling the cellular microenvironment, Alvéole presents its first device PRIMO. Alvéole was founded in 2010 by three researchers from CNRS* in collaboration with Quattrocento, a “creator of young innovative companies” in the life sciences field that allows academic researchers to transform their inventions into commercial products. Vincent Studer (a specialist in bio-engineering), Maxime Dahan …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

7 0 7 14
ManRos Therapeutics ManRos Therapeutics

From Sea to Pharmacy ManRos Therapeutics is a biotech company identifying, optimizing and characterizing innovative, low molecular weight kinase inhibitors for the treatment of cystic fibrosis. ManRos was founded in 2007 and is led by Dr Laurent MEIJER, Chairman and CSO, former distinguished Director of Research at the CNRS, and Dr Philippe de Lavenne, CEO, former Vice-President at Actelion Pharmaceuticals. For 40 years, Dr Meijer dedicated his research to the study of protein kinases and their inhibitors, mostly at the CNRS. Drug Development, Cystic Fibrosis, and Biotechnology

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

2 2 0 5
Depixus Depixus

Depixus SAS, based in Paris, is a life science technology company pioneering a groundbreaking technology based on magnetic force spectroscopy. This innovative technology provides real-time analysis of individual biomolecular interactions at scale, enabling researchers to decode disease mechanisms and unlock faster routes to more effective therapies. Single molecule analysis, RNA Drug Discovery, Protein-protein Interaction Analysis, Biophysics, Drug Discovery, Compound Screening, biomolecular interactions, and interactomics

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

2 2 0 63
Remedee Labs Remedee Labs

Redefining Life with Chronic Pain Remedee Labs aims to change people’s lives thanks to a patient-centric digital service platform using the first endorphin stimulator. 1.5 billion people worldwide suffer from chronic pain and over half of them are not satisfied with their care. Remedee Labs aims to give these patients a new life. Based on 10 years of pre-clinical and clinical research, Remedee Labs has developed the first endorphin stimulator for personal use. Building on the experience of its clinical partners, the company now uses its unique technology to offer the first patient-centered digital service platform for chronic pain management, …

Type: Startup Activities: biotech deeptech Technologies: SaaS

30 12 15 34
GAOMA Therapeutics GAOMA Therapeutics

Bioactive Lipids: the Future for Breakthrough Therapeutics GAOMA Therapeutics is a biotech company specialized in the development of lipids derivatives as innovative therapeutic molecules. Lipids are a class of compounds that has been largely under-exploited, whereas it plays a key role in many medical conditions. GAOMA has the ambition to tap into the therapeutic potential of lipids. The company’s first drug candidate, GAO-3-02, is a novel patented active ingredient. It aims to address epilepsy and cognitive disorders, by targeting neuroinflammation and brain plasticity. In various preclinical experiments, GAO-3-02 has thus demonstrated its ability to limit seizures, protect and restore cognitive …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

1 1 0 5
ExactCure ExactCure

Our Digital Twin simulates the concentration of drugs in the blood of patients, based on their personal characteristics. ExactCure provides a personalized eHealth software solution. Our VISION is to live in a world where each individual has access to a personalized medication. Our MISSION is to predict the personalized effects and interactions of drugs within the body of each individual. Problem: Inappropriate medical treatments sometimes cause illness. This “iatrogenic” side effect leads to 20,000 deaths and costs €10 billion per year to the public healthcare system in France alone. Worldwide, it probably leads to more than 1 million deaths and …

Type: Startup Activities: healthtech deeptech biotech Technologies: A.I.

43 22 24 23
OPIA Technologies OPIA Technologies

OPIA Technologies is a company dedicated to the development of medical devices with a specialization in ophthalmology but also provides services for medical devices compagnies. One of the main goals is to provide innovative and reliable devices to improve the diagnosis and care of patients with ocular diseases. OPIA is building a complete portfolio of medical devices for sampling ocular surface components (conjunctiva: EYEPRIM , tear film: TEARPRIM) and for non-invasive ocular drug delivery (IONTOFORVET), based on proprietary patents. Activities encompass the whole life cycles of the devices. The team of Opia design, manufacture and warrants the regulatory and quality …

Type: Startup Activities: deeptech healthtech biotech manufacturing Technologies: Synthetic Biology

0 0 0 2
Mimitika Mimitika

[Automatic translation follows] Inspired by summer, made for everyday Follow our adventures #forsunlovers vegan • cruelty free • made in france Mimitika is the first lifestyle sun protection brand for sun lovers. We offer quality products, formulated and produced in France with care and in a good mood. Our mission is to make the people we love want to protect themselves with pleasure to tan well. That's why we offer creams with impeccable protective properties but with a texture as light and pleasant as a day cream. And to fulfill our mission, our products contain a marine active ingredient that …

Type: Startup Activities: cosmetics biotech deeptech manufacturing Technologies: Bio sourced materials

3 2 1 9
MT-act MT-act

FROM DISCOVERY TO THERAPEUTICS MT-act is a CNRS spin-off. #techtransfer We develop class compounds to treat human pathologies that share a common molecular defect; dysfunction of the skeleton of the cells called microtubules - abbreviated MT. Stiffening of the skeleton of our cells is a central disease driver. That is why we act on them. We developed a technology platform to charter an entirely neglected pharmaceutical space. MT-act prioritizes indications based on scientific evidence, proven unmet medical needs and where the roadmap to patients is feasible and desired. Drug development, Microtubules, Tubulin code, Preclinical, Drug screening, first-in-class, and drug discovery

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

2 1 1 7
CellProthera SAS CellProthera SAS

Pionnier de la thérapie régénératrice cardiaque CellProthera, a biotechnological company, has developed a unique therapeutic technique which enables the structural and functional regeneration of severe post-infarctus cardiac lesions. After European and national (FR/GB) authorization was obtained , CellProthera has started its I/IIB clinical trial in Humans. Heart Regeneration

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

14 7 6 30
PROFILEHIT PROFILEHIT

An innovative profiling company ProfileHIT is a French CRO exploring the pharmacological properties of new compounds, coming from natural products (algae, mushrooms, plants...), Medicinal Chemistry, Biotechnologies or from Agro-Food Industry. Thanks to an innovative detection-method by flow cytometry, ProfileHIT brings an early access to the biological potential of new molecules. Based on a high-quality and innovative technology, ProfileHIT provides an early access to the therapeutic potential of a molecule, allowing a fast determination of its future clinical uses, targets or indications. Furthermore, this screening-strategy enables the exclusion from the pipeline of some of the compounds which would present toxicities over …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

1 1 1 4
Advanced BioDesign Advanced BioDesign

Overcoming Tumor Drug Resistance Founded in 2010, Advanced BioDesign is a clinical stage company developing a highly promising therapy for cancer with high unmet medical needs. Advanced Biodesign has developed a therapeutic approach based on a selective inhibition of ALDH enzymes. Advanced Biodesign project consist in the development of small-molecule that will selectively inhibit specific ALDH enzyme. By targeting this family of enzyme, will block specifically the intracellular mechanism of detoxification that cancerous cells have developed in order to escape form the programmed cell death called apoptosis. Oncology

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

6 1 4 22
Ermium Therapeutics Ermium Therapeutics

Controlling auto-immune diseases Ermium Therapeutics is a discovery stage Biotechnology company developping innovative therapies for auto-immune diseases

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

2 2 0 6
ETISENSE ETISENSE

Jacketed physiological monitoring for life sciences Etisense, is a Lyon (FR) based MedTech company specialized in non-invasive physiological monitoring. Etisense develops unique instrumentation solutions for pre-clinical research and development. DECRO, (www.etisense.com),our 1st product is now available to help scientists to perform pre-clinical research differently. recherche, R&D pharmaceutique, Instruments connectés, Plateforme d'acquisition de signaux physiologiques, Logiciel, and Electronique embarquée

Type: Startup Activities: biotech deeptech manufacturing

4 1 3 15
Diotheris Diotheris

Diotheris develops anti-infective microbes to prevent bacterial infections and act against antibiotic resistance We create bacterial therapies of the human skin and mucosal microbiome against pathogenic bacteria. Our first suite of products (NASOFLORE line) targets Staphyloccocus aureus / MRSA (Methicillin resistant S aureus). The products based on live bacteria identified in our clinical and in vitro studies do not generate emergence of antibiotic resistance. antimicrobial, nose microbiome, therapeutics, LBP, Staphylococcus Aureus, and MRSA

Type: Startup Activities: deeptech biotech healthtech Technologies: Synthetic Biology

1 1 0 1
Blue Bees Therapeutics Blue Bees Therapeutics

Blue Bees Therapeutics develops immunomodulatory proteins with therapeutic potential to fight cancer Blue Bees Therapeutics is a biotechnology company founded in March 2022, dedicated to the development of first-in-class immunotherapies for the treatment of cancers, based on a breakthrough technology discovered by the team led by Dr Michel Léonetti, within the Department of Pharmacology and Immunoanalysis from CEA Paris-Saclay. This technology allows to generate antibodies stimulating the anti-tumor immune response via a double cell receptor targeting coupled with heparan sulphate proteoglycans (HSPG). Immunothérapie, Immuno-oncologie, pharma, Biotech, Immunologie, Oncologie, Cancer, Médicament, and Drug

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

7 4 0 8
Enterome Enterome

Delivering the promise of immunotherapy Enterome is a clinical-stage biopharmaceutical company developing breakthrough immunomodulatory drugs for the treatment of cancer and immune diseases. Enterome’s pioneering approach to drug discovery is based on its unique and powerful bacterial Mimicry drug discovery platform, which allows it to analyze and uncover new biological insights from the millions of gut bacterial proteins in constant cross-talk with the human body. The company is currently developing a pipeline of drug candidates consisting of OncoMimicsTM peptide-based immunotherapies for the treatment of cancer. EO2463 is in a Phase 2 clinical trial for indolent non-Hodgkin lymphoma, demonstrating a benign …

Tags: FrenchTech2030 Type: Startup Activities: healthtech biotech deeptech Technologies: Synthetic Biology

14 6 8 78
BrainPlotting BrainPlotting

Human PK data from preclinical stages BrainPlotting is a french contract research organization company which offers his knowledge to predict the entrance of drugs into the brain To that end BrainPlotting developped in vitro models based on fresh human tissus and cells. BrainPlotting is incubated at the Brain and Spine Institute (ICM), Paris, France Our core business is the study of pharmacokinetics (PK) in the human brain. The molecules that we study can have CNS targets as well as peripheral targets. To study the brain's PK, BrainPlotting uses the most accurate predictive models and the most recent methods and tools. …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

0 0 0 1
InBrain Pharma InBrain Pharma

InBrain Pharma, a CNS disorders focused biotech, founded in 2018, exploiting through an exclusive worldwide patent license signed with the Northern France TTO, a groundbreaking therapeutic approach of advanced Parkinson’s Disease based on the research work of Pr David DEVOS and Pr Caroline MOREAU developed within their academic research Team from the Université́ de Lille, Lille Neuroscience & cognition UMR-S 1172 INSERM and the Lille University Hospital. To date, the company has raised €4.4 million in dilutive and non-dilutive financing, these funds having enabled to carry out a first phase I/IIb DIVE-I clinical trial on 12 patients, for which results …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

13 5 9 5
Biocellvia Biocellvia

Biocellvia evaluates the efficacy of your lead molecules from histological slides thanks to our digital technology Biocellvia is a french digital pathology company developing Intelligent Image Analysis solutions for pharmaceutical industry (Big Pharma, Biotechs, CRO) and academic communities involved in R&D. We have developed digital image analysis solutions, that enable to evaluate fully-automatically the level of efficacy of your lead molecules thanks to histological slides (in vitro, ex vivo, biopsies) in various pathologies such as: - Gastrointestinal (NASH, Liver fibrosis) - Respiratory (IPF, COPD, PAH) We provide image analysis as a service. Our technology evaluates your molecules with more accuracy, …

Type: Startup Activities: biotech deeptech Technologies: A.I. A.I. - Image Processing

8 1 7 6
MYRIADE MYRIADE

Reveal the invisible Myriade is a French company created in 2017 that develops an innovative nanoscale imaging technology. Based on the works of the Langevin Institute, a French academic laboratory specialized in optical and ultrasonic technologies for life sciences, the technology Videodrop relies on a single-arm interferometric technique. It makes it possible to visualize without labeling living nanoparticles such as viruses, phages, or extracellular vesicles. The process was developed by Professor Claude Boccara at the request of the Professor Martine Boccara, specialist in virology, who was looking for a quick method to list viruses present in seawater samples collected during …

Type: Startup Activities: biotech deeptech

3 2 1 29
NanoMedSyn NanoMedSyn

NanoMedSyn develops a new delivery platform to create first-in-class drugs by the engineering with patented AMFA vectors NanoMedSyn was born from the fundamental research of its biologist and chemist founders who discovered a breakthrough technology for drug delivery to the lysosomal cell compartment leading to potentiation of therapeutics. This technology, validated at the preclinical level, has a wide range of applications in the fields of oncology, immunity, inflammation or metabolism. NanoMedSyn’s development plan is based on a strong intellectual property of patented synthetic derivatives called AMFA. The main application is the engineering of recombinant proteins like antibodies or enzymes for …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

0 0 0 4
IMD-Pharma SAS IMD-Pharma SAS

Rebalancing the immune system, resolving inflammation. Drug candidates from our molecular platforms normalize the immune system by downregulating pro-inflammatory immune response and upregulating regulatory immune response. IMD-Pharma S.A.S is a french biotechnology company conducting research and development of innovative drug candidates for immune-related inflammatory diseases. Founded in 2016, IMD-Pharma is a company from the Laboratoire de Chimie de Coordination (CNRS) and the Centre de Physiopathologie de Toulouse Purpan (INSERM/CNRS/Université Toulouse III). immuno-modulation, anti-inflammatory drugs, chronic inflammatory diseases, Multiple Sclerosis, Rheumatoid Arthritis, dendrimers, monocyte rehabilitation, and psoriasis

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

1 0 1 7
KDBIO s.a.s. KDBIO s.a.s.

European Distributor of innovative cell culture products KDBIO is distributing advanced cell culture devices used for producing monoclonal antibodies, and 3D culture plates for generating multiple spheroid replicates per well, as well as 3D culture plates with nanofiber scaffolds. Business Development, Sales, Marketing, and Distribution

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

0 0 0 1
Intellisness Intellisness

Market Research, Competitive Intelligence, IP Intelligence Exclusively for the Life Sciences Community Specialised in life sciences, we help you make the best decisions by bringing you all the necessary market, scientific, and patent information. Our bias is clear. Our industry is structured around three pillars: science, markets, and industrial property. To only take one side of this trilogy into account can lead to erroneous conclusions. It’s for this reason that we’ve created a company capable of integrating those three dimensions. Our Scientific Committee is one example. Even though we invest heavily in technologies such as datamining, databases, and other tools …

Type: Startup Activities: legaltech biotech deeptech martech Technologies: Data Analytics

0 0 0 1
BioMiMetiC BioMiMetiC

[Automatic translation follows] Bio-waste recovery solution by entomo-conversion BioMiMetiC is the only company that designs integrated solutions for the recovery of bio-waste via the mass production of insects. Entomo-production, Bio-waste recycling, Biotechnology, Plant nutrition, Animal nutrition, Social and Solidarity Economy, CSR, Environment, Circular Economy, Agriculture, and Agri-food

Type: Startup Activities: cleantech civictech agritech biotech deeptech greentech manufacturing

7 8 0 6
Deemea Deemea

Get insights from your imaging data Deemea is a digital health company with expertise in the AI-driven structuring and analysis of medical data. Our specialization in imaging data processing has led us to develop and deploy a collaborative platform for medical data analysis, aimed at expediting biopharmaceutical and medical device clinical studies. Our innovative proprietary technology powers a multi-modal, multi-centric platform that prioritizes the security, privacy, and sovereignty of medical data, as well as the sustainability of healthcare facilities. Deemea empowers data-driven research, ultimately expediting patients' access to innovative therapies.

Type: Startup Activities: healthtech deeptech biotech Technologies: Data Analytics

27 5 26 17
AbLeads AbLeads

AbLeads is a young biotech startup developing innovative solutions in Oncology, through the generation of novel, personalized therapeutic antibodies. Learn More on https://ableads.fr Biotechnology, Oncology, Immunotherapy, Therapeutic Antibodies, and Personalized Medicine

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

0 0 0 1
LYMPHOBANK LYMPHOBANK

[Automatic translation follows] Ready-to-use cell bank, for research, for patients Lymphobank - ready-to-use cell bank, for research, for patients. Lymphobank is a biotech company specializing in the supply of adult and placental blood cells for research use, the characteristics of which will be available online (www.lymphobank.fr), allowing the choice of the cell product according to a donor of interest. Our services are focused on the development of cellular immunotherapy products. In addition, Lymphobank is developing an innovative approach to allogeneic adoptive immunotherapy for hepatocellular carcinoma (the most common liver cancer and the second leading cause of cancer-related death worldwide, with …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

4 2 2 5
Odimma Therapeutics Odimma Therapeutics

Empowering Personalized Immunotherapy to Treat Cancer Odimma is a French biotech company with a unique approach in active personalized cancer immunotherapy. Immunotherapy has revolutionized the treatment of many advanced cancers. Despite this amazing achievement, significant clinical benefits are still limited to 10 to 30% of patients. Odimma believes in the future of precision medicine, and leverages recent advances in the field of immuno-oncology to amplify the efficacy of current therapies, improving lives and making each patient unique. By harnessing the ability of the patient’s own immune system to specifically recognize non-self-targets displayed by the tumor, also called neoantigens, Odimma has …

Type: Startup Activities: deeptech biotech manufacturing Technologies: Synthetic Biology

10 3 8 7
Feeligreen Feeligreen

Dermo-innovation Feeligreen is a technology startup developing safe and effective micro-current devices for a wide range of cosmetic and therapeutic applications. With applications ranging from anti-ageing to wound healing, it develops and sells innovative drug-delivery systems to TIer1 pharmaceutical laboratories medical devices, therapeutics, cosmetics, and skincare

Type: Startup Activities: healthtech deeptech biotech manufacturing Technologies: Synthetic Biology

12 7 2 4
CliniSciences Group CliniSciences Group

Reagents and instruments for immunology, cell biology and molecular biology. CliniSciences commercialises reagents (antibodies, recombinants, ELISA kits, RNAi, cDNA clones, probes, PCR/qPCR reagents...) to diagnostic and research labs. As very dynamic company, we do our best to be close to our customers'​ needs in terms of high quality reagents that we propose and in terms of service that we provide (search for a particular antibody, technical support, delivery time, etc.) Our principal assets for better serving you : adaptability, flexibility, reactivity and naturally the competence of the technical specialists at your service.

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

8 5 1 73
NANOBACTERIE NANOBACTERIE

NANOBACTERIE is a biotechnology company based out of 36 BOULEVARD FLANDRIN, PARIS, France. It develops a cancer treatment using natural iron oxide nanoparticles (called magnetosomes) that are introduced to tumors and heated. Nano-medicine, Oncology, hyperthermia, Prostate tumor, breast tumor, sarcoma, head and neck tumor, and glioblastoma

Type: Startup Activities: deeptech biotech

0 0 0 3
Kallistem Kallistem

Kallistem is a biotech company specialized in spermatogenesis. The company was founded in 2012 with the objective to anticipate and treat male infertility. It promotes a technology and expertise developed by Philippe Durand and Marie-Helene Perrard, two internationally renowned scientists in the field of the reproductive biology and more specially in in vitro spermatogenesis. Kallistem has developed, in collaboration with its partners, original and innovating technologies of germinal cell culture for male fertility preservation and the treatment of male infertility. male fertility, cellular therapy, biology of reproduction, and testicular toxicology

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

0 0 0 3
In-Spir In-Spir

[Automatic translation follows] Olfactory branding. Improve comfort and well-being in your spaces. Natural and organic fragrance diffuser 🇫🇷 In-Spir, Olfactory Branding. Give a new dimension to your spaces thanks to the olfactory, our most emotional sense. Improve the well-being and comfort of your customers, employees and patients. Natural and organic fragrances for a responsible experience. Connected and professional diffusers for an extraordinary experience. We help you create your olfactory identity to strengthen your brand image in your store, business, salon. Add a zen atmosphere to your hairdressing salon, beauty salon. Reduce the anxiety of your patients in the waiting room …

Type: Startup Activities: biotech healthtech proptech deeptech Technologies: IoT Bio sourced materials

4 2 1 2
aKen Medical aKen Medical

The Next-generation of personalized and adaptive radiotherapy. αKen Medical is a biotechnology company aiming to develop and bring to market the Next-generation of personalized and adaptive radiotherapy for treating solid cancer tumors. The proposed therapies seek to improve the effectiveness of alpha therapy and reduce its side effects. Radiotherapy, Cancer treatment, Brachytherapy, Targeted therapy, Biotechnology, Medical devices, Alphatherapy, Nanotechnology

Type: Startup Activities: deeptech biotech

7 3 2 3
Kolibri Kolibri

Playing music to cells Kolibri revolutionises the way we grow and engineer cells at scale using acoustic waves. 🔍 Book a discovery call: https://calendly.com/tamsin_kolibrilab/discovery-call Showing 10x increase in cell density and 50x reduction in production costs, our patented bioreactors help our partners in drug development unlock patient access to gene therapies, with a proof of principle in AAV gene therapy. Being cell-agnostic and scalable, our process has significant potential across a range of high-value cell-based therapies - or in the cellular agriculture space more broadly. gene therapy, biomanufacturing, cellculture, acoustics, hardtech, and biotech

Type: Startup Activities: biotech deeptech manufacturing Technologies: Synthetic Biology

13 3 10 14
AIS BIOTECH AIS BIOTECH

A nature-inspired solution to trap pathogens @AIS Biotech (with AIS for Anti Infective Sugar) is a French Biotech company based in the @Région Auvergne-Rhône-Alpes, France, incorporated in March 2023 with the objective of developing a new class of sugar-based anti-infective biotherapeutics to fight (re)emerging infectious diseases. Thanks to a Bioengineering plateform based on the expertise of the leading edge academic laboratory @CERMAV (@CNRS, @UGA, Grenoble, France), AIS Biotech aims to develop a pipeline of innovative sugar-based biopharmaceuticals which can prevent or treat infections by mimicking the natural host surface oligosaccharide binding-sites of pathogens. GlycoFlu, our first drug-candidate validated at the …

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

18 7 13 5
YLMSPORTSCIENCE YLMSPORTSCIENCE

YLMSPORTSCIENCE is a publishing company based out of ENTREE A3 RESIDENCE LE PRESIDENT 97 BOULEVARD CARNOT, NICE, France.

Type: Startup Activities: biotech

1 0 0 2
LiMM Therapeutics LiMM Therapeutics

LiMM is the biopharmaceutical company harnessing the molecular cross-talk between neuronal and innate lymphoid cells. LiMM is the biopharmaceutical company harnessing the molecular cross-talk between neuronal and innate lymphoid cells within peripheral tissues. By decoding the language of the neuroimmune cross-talk, we are developing first-in-class therapeutic products – NRILs: neuronal reprogrammers of innate lymphocytes - to preserve health and treat inflammatory, infectious and metabolic diseases. We are bridging neural sensing and immunology discoveries to unlock therapeutic solutions for the benefit of patients.

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

0 0 0 4
FunCell FunCell

TECHNOLOGY FunCell Technology is bio inspired and use biobased polymers to enhance cellulose-cellulose interactions in wet and dry conditions. Our additives show a high degree of mechanical performances: papers are up to 2 times stronger at dry state and up to 20 times stronger at wet state. The high reactivity of the product also allows a further functionalization in aqueous medium to provide on demand functionalities to the final product. APPLICATIONS FunCell propose additives that are suitable for all kind of cellulosic materials. They offer sustainable solutions for paper and boards, for all kinds of fibers and pulps. ADVANTAGES FunCell …

Type: Startup Activities: biotech deeptech manufacturing Technologies: Bio sourced materials New Materials

16 6 13 21
AberActives SAS AberActives SAS

[Automatic translation follows] Biorefining marine algae for nutraceuticals and cosmetics AberActives is a marine biotechnology company Our laboratory is located on the Laber site in the premises of the Roscoff marine station, a global center of excellence in fundamental research on algae. The start-up proposes the use of bacterial enzymes to transform algal sugars with a view to manufacturing ingredients in cosmetics and/or health nutrition.

Type: Startup Activities: deeptech biotech greentech manufacturing

10 3 0 8
BIOMILLENIA BIOMILLENIA

Microbiology assays at previously impossible speeds and strain banks with amazing diversity ! Microbiology is what we do. Our unrelenting focus has enabled us to develop unique capabilities in ultra-high-throughput single-cell culture of microorganisms. Businesses in areas as diverse as pharma, agriculture, food, human health and environmental protection have partnered with us to gain powerful competitive advantages from our technology.So could yours. Our proprietary microfluidic platform is capable of : - identifying microbes of interest based on their functional characteristics among millions of candidates - perform a wide range of assays at previously impossible speeds - generate strain banks with …

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

0 0 0 3
Deeptope Deeptope

Advanced Antibody Expertise Deeptope's expertise lies in antibody charaterisation (epitope/paratope mapping) and optimisation using high throughput methods. antibody, paratope mapping, epitope mapping, and antibody optimisation

Type: Startup Activities: biotech deeptech healthtech Technologies: Synthetic Biology

2 2 0 7
SeaBeLife Biotech SeaBeLife Biotech

Solutions to deprogram cell death : A breakthrough innovation to treat and prevent severe pathologies We develop small molecules that inhibit regulated necrosis using an original mechanism of action. Regulated necrosis is one of the recently identified pathophysiological factors in many diseases with severe outcomes. The technical, therapeutic and economic potential is major. Our activity focuses on the development of drugs inhibiting regulated necrosis, from the selection of the molecule to the proof of efficacy in the patient. We focus on acute and orphan diseases because preclinical and clinical development is facilitated, allowing proof of concept (POC) to be provided …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

18 4 15 15
MB Therapeutics MB Therapeutics

3D printed personalized medicines MB Therapeutics is a pharmaceutical company that offer patient centric solutions to Develop and produce personalized medicines. MB Therapeutics solution is powered by 3D printing, allowing dosage, shape and API customization in GMP environement Pharmaceutical development, Pharmaceutical 3D printing, and Personalized medicines

Type: Startup Activities: biotech deeptech healthtech Technologies: Synthetic Biology

8 3 6 8
KUSTE BIOPHARMA KUSTE BIOPHARMA

KUSTE is a Clinical Stage Biopharma Company founded by seasoned entrepreneurs in Life Science KUSTE is a Clinical Stage Biopharma Company founded by seasoned entrepreneurs in Life Science with the aim of tackling major chronic inflammatory diseases

Type: Startup Activities: biotech deeptech

1 1 0 1
SMARTOX SMARTOX

Smartox Biotechnology is specialized in peptide research and manufacturing Smartox Biotechnology is specialized in peptide research and engineering. Peptide synthesis, physiology, pharmacology, neuroscience, ion channel research, toxin, venomous animals, and screening library

Type: Startup Activities: biotech deeptech manufacturing Technologies: Synthetic Biology

0 0 0 7
Saxol Saxol

Neuroprotecting Patient's Future Saxol, newborn company develops innovative compounds able to fight and/or to prevent peripheral neuropathies, including Diabetes peripheral neuropathies, Immuno and Chemotherapy-Induced Peripheral Neuropathies (CIPN). Based on IAB research on Carbazole structure (Lafanechère Team) and with the support of Linksium, we plan to bring to patients, new neuroprotective drugs to answers current Unmet Medical needs CARBA1, our lead compound, has a dual pharmacological activity. 1 CARBA1 has neuroprotective activity through a mechanism of regulation and reactivation of energy production at the cellular level. 2. It enhances the action of chemotherapies, especially those based on taxane, achieving the same …

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

3 3 0 1
BIOptimize BIOptimize

BIOptimize is a company that delivers data mining tools and predictive models, using a specific methodology, focused on exhaustivity, simplicity and interactivity. BIOptimize is winner of the NETVA 2013 competition and the French Senate competition "Tremplin d'Entreprises" 2013 as being the best and more innovative and promising french company in the field of biotechnology Specialized in the detection of hidden informations in the scientific data, BIOptimize technology misses not any important information in your scientific data, from in silico Drug Discovery to Clinical Trials Opimization. BIOptimize developped an online sofrware BIOpticloud that can instantly analyze and expalin all your data, …

Type: Startup Activities: biotech deeptech Technologies: A.I. A.I. - Machine Learning Data Analytics

5 2 3 1
KCAS Bio - Lyon KCAS Bio - Lyon

Science Accelerated KCAS Bio - Lyon (Active Biomarkers) operates as a bioanalytical laboratory based in Lyon, France and headquartered in Olathe, Kansas, USA. We offer comprehensive service solutions for the development of both large and small molecules, with extensive capabilities and expertise in pharmacokinetics, immunogenicity, soluble and cellular biomarker analysis for clinical trials. Operating in state-of-the-art BSL2 facilities, our company is GLP certified and ISO 9001:2015 certified, with a unique track-record in the development, validation, and implementation of analytical methods. Our expert team has supported hundreds of studies in multiple therapeutic areas: oncology, infectious diseases, inflammatory pathologies, and neurodegenerative diseases. …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology Data Analytics

2 1 2 31
BiPER Therapeutics BiPER Therapeutics

First in class small molecules pushing cancer cells to burn out BiPER Therapeutics is developing a first-in-class pipeline of therapeutics overstressing cells to cure patients. The company’s lead compound, BPR001, is a first-in-class small molecule therapeutic targeting BiP, an oncogenic protein shown to have a critical role in cancer

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

10 6 9 7
Kimialys Kimialys

Innovative biosensing solutions for diagnostic and pharmaceutical companies, leveraging our K-One® surface chemistry. We are a team of chemists and biosensor engineers gathered around a common mission: shaping the future of biodetection for a better world. Kimialys is the result of 10 years of meticulous academic research in surface chemistry. Controlling what is happening on the surface is a fundamental aspect of biosensing techniques such as rapid tests, point-of-care diagnostics, and real-time sensors. Without the right surface interactions, even the most advanced biosensors can falter, leading to misleading results. Our research efforts have always been to optimize these crucial parameters, …

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

13 4 6 17
Zionexa Zionexa

Targeted imaging and therapies Zionexa is an international and innovative company developing and commercializing molecular imaging solutions, in-vivo biomarkers for targeted therapies in oncology, to improve patients’ pathway and bring them a better quality of life. Molecular Imaging, Oncology, Targeted therapies, CDx, Radiopharmaceuticals, and Biomarkers

Type: Startup Activities: biotech deeptech

0 0 0 6
OREGA Biotech OREGA Biotech

Discovery of novel immune checkpoint inhibitors for cancer immunotherapy OREGA Biotech specializes in the discovery and the development of first-in-class monoclonal antibodies for cancer immunotherapy. The company was incepted in 2010 and is managed by Jeremy Bastid, CEO and Gilles Alberici, President. The science at OREGA Biotech is based on the research conducted by its academic cofounders Nathalie Bonnefoy, Armand Bensussan and Jean-François Eliaou. Our in vivo screening approach aims at discovering and validating novel immune checkpoint inhibitors and regulators of anti-PD1 response. Our lead asset, an anti-CD39 monoclonal antibody, has been out-licensed to Innate (2016) Pharma and then partnered …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

0 0 0 8
Advicenne Advicenne

Pathbreaking treatment for rare diseases. Advicenne is a specialty pharmaceutical company dedicated to improving the lives of patients who suffer from rare renal diseases. Advicenne have spent more than 10 years developing products for the treatment of rare renal diseases. At Advicenne, we are committed to developing and commercializing medicines that are suitable for both children and adults – groundbreaking treatments for rare diseases should be available to patients of all ages. Laboratoire Pharmaceutique

Type: Startup Activities: biotech deeptech

0 0 0 24
[IS]2 [IS]2

Innovative Solutions for Instrumentation and Science You have a need in science or technology? We certainly have the solution you need at the best price and above all the shortest delay! Whether it is a simple proof of concept using numerical simulation or the development of a complex operational prototype, we will bring you the right solution for your needs. Instrumentation and Proof Of Concept

Type: Startup Activities: biotech deeptech it services

0 0 0 1
ENZYNOV ENZYNOV

[Automatic translation follows] The power of enzymes (white biotechnology) in the service of detergency ENZYNOV is a young international company invested in the biotechnological innovation of enzymatic eco-solutions and their applications for professionals. Economical, ecological and efficient, our eco-solutions are risk-free for your employees and our environment. They are applicable to all sectors of activity. We support our customers in France and the United States in optimizing their natural cleaning processes by facilitating surface maintenance thanks to our biocatalysts in the sectors of industrial production, ERP, the agri-food industry, the oil industry, etc. Contact us to benefit from a personalized …

Type: Startup Activities: biotech civictech deeptech manufacturing Technologies: Bio sourced materials

3 0 3 4
MAAsiRNA MAAsiRNA

MAAsiRNA develops a pioneering targeted therapy utilizing small interfering RNA (siRNA). A significant challenge in the field of nervous system pathologies lies in the absence of effective treatments. MAAsiRNA develops a pioneering targeted therapy utilizing small interfering RNA (siRNA). After over a decade of intensive interdisciplinary research, we have successfully developed a siRNA-based treatment for Charcot-Marie-Tooth disease type 1A (CMT1A), the most prevalent form of hereditary peripheral neuropathy. CMT1A affects 1 in 5000 people, comprising a total of 1.5 million individuals worldwide. Our current objective is to advance towards a patient-ready therapy. Our innovative therapeutic approach has the potential to …

Type: Startup Activities: deeptech biotech healthtech Technologies: Synthetic Biology

1 1 0 5
Abivax Abivax

Abivax is a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases. Abivax is currently evaluating its lead drug candidate, obefazimod, in Phase 3 clinical trials for the treatment of moderately to severely active ulcerative colitis. Abivax also plans to initiate a Phase 2a clinical trial of obefazimod in patients with Crohn’s disease. Obefazimod is an investigational, orally administered, once-daily therapy, which we believe has the potential to be a differentiated treatment option for inflammatory bowel diseases. It is the first and only molecule …

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

9 5 5 81
NaoX Technologies NaoX Technologies

[Automatic translation follows] A laboratory in the ear NaoX Technologies is a French startup launched in 2018 by Hugo DINH, Polytechnician and Michel LE VAN QUYEN, expert in neuroscience at Inserm. Our mission is to democratize the prevention of neurological disorders. Neuroscience, IOT, and Health & Well-being

Type: Startup Activities: biotech deeptech healthtech Technologies: IoT

20 3 18 21
CYNBIOSE CYNBIOSE

Exploring together! We support biopharmaceutical research with translational preclinical models. CYNBIOSE is France-based non-clinical research organization. Preclinical CRO, Pharmacokinetics, POC, Efficacy, Immunotherapies, Drug, Early tox, CNS, Infectious diseases, Respiratory diseases, Non clinical, CRO, PK, PD, and TK

Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

8 3 5 20
Xegen Xegen

Biostatistics & Bioinformatics company specialized in Next Generation Sequecing data analysis Xegen is a bioinformatics company specialized in Next Generation Sequencing (NGS) data analysis. We provide support for our customers or partners in their NGS data processing issues, through specific, automated, high added value bioinformatics analyzes. Xegen is developing Polypheme a bioinformatics suite dedicated to complex genes analysis (polymorphisms detection or allelic types). Polypheme analysis includes in particular HLA Typing, classic (HLA-A, -B, -C, DRB1, DQB1) and not classic genes (HLA-E, -F, -G, -H). Polypheme is also used to discover new alleles. Bioinformatics, Genomics, Typing, HLA, Diagnostics, NGS data analysis, …

Type: Startup Activities: biotech deeptech Technologies: Data Analytics

9 0 9 3
Skintifique Skintifique

[Automatic translation follows] Your Universal Hydration Companion for your Skincare at all stages of your life and for all your needs Your Universal Hydration Companion for your Skincare at all stages of your life and for all your needs 🌱 Yuka Score “Excellent” 🐣 Vegan ✨ Effective 🇫🇷 Made in FR 👨‍👩‍👧‍👦 Mixed & all skin types skincare, dermatology, laboratory, sensitive skin, allergic skin, innovation, bioinspiration, and science

Type: Startup Activities: biotech cosmetics deeptech

1 1 0 9
SPIMA Therapeutics SPIMA Therapeutics

Unlocking New Immunotherapy Paths with Smart Peptides SPIMA Therapeutics emerges as a spin-off from the University of Montpellier, France, uniting experts in cutting-edge peptide chemistry and inflammation biology. SPIMA focuses on developing innovative peptide-based immunotherapies for challenging targets, particularly protein-protein interactions. Our lead program is a Stapled Peptide targeting the Myddosome complex. This innovative approach holds immense promise for revolutionizing treatments in inflammatory and oncological diseases, offering hope where it's needed most. SPIMA Therapeutics is part of the nexus of Landmark Bioventures. Join us in shaping the future of medicine, where discovery meets dedication. Immunothery

Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

1 1 1 3
Parean Biotechnologies Parean Biotechnologies

Deep Immune Phenotyping & MultiOmics DataScience, for immune precision medicine Parean Biotechnologies is a pioneering service company dedicated to advancing preclinical and clinical programs in the field of oncology and immune related diseases. Our comprehensive approach integrates an in-house wet lab (cytometry, cell sorting, libraries generation in bulk or single cell protocols) and a cutting-edge data science unit to drive innovation and foster transformative breakthroughs. Key offerings includes: - Deep Immune Phenotyping Expertise: Acting as an interim research team, we provide unparalleled proficiency in deep immune phenotyping, with a focus on T-Cell, B-Cell, NK, and other immune cell subsets. - …

Type: Startup Activities: biotech deeptech Technologies: Data Analytics

4 2 0 8