Value proposition

Analysis of proteins and small molecules leading to crystallization trials for academic and commercial users.

The project “Core facility for crystallographic and biophysical research to support the development of medicinal products” is funded by the TEAM-TECH Core Facility programme from the Foundation for Polish Science. The project establish a Core Facility for Crystallography and Biophysics (CFCB) at the Biological and Chemical Research Centre, University of Warsaw under the supervision of Prof. dr hab. Krzysztof Woźniak (Manager) and dr eng. Jan Kutner (Deputy Manager).
The mission of the Core Facility for Crystallography and Biophysics (CFCB, UW) is the analysis of proteins and small chemical compounds (molecules) leading to crystallization trials for academic and commercial users. The project enable the study of challenging biochemical and pharmaceutical problems, with emphasis on drug development and collaborations with the local research groups. Work at CFCB will be carried out in an interdisciplinary way, including both wet chemistry (CHEM) and biology (BIO) techniques, as well as theoretical approaches including structure modelling, bioinformatics and computational methods. BIO and CHEM team members work in synergy complementing their knowledge, skills and experience. Apart from services and collaborations, postdoctoral and PhD researchers carry out their own research projects in either small-molecule or protein crystallography.

Protein Crystallography, X-Ray Structure Analysis, Small Molecule Crystallography, Drug Discovery, Ligand Binding, DSC, TGA, Polymorph analysis, Polymorph screening, Protein purification, Biochemistry, Biophysics, Electron density, Phase transition, Cryo-EM, and Cryo-TEM