Entity
Description
  • Value proposition

    Bringing a novel class of Butyrophilin-targeted checkpoint modulators into the clinic

    ImCheck Therapeutics is designing and developing a new generation of immunotherapeutic antibodies targeting butyrophilins, a novel super-family of immunomodulators.

    As demonstrated by lead clinical-stage program ICT01, which has a mechanism of action to simultaneously modulate innate and adaptive immunity, ImCheck's “first-in-class” activating antibodies may be able to produce superior clinical results as compared to the first-generation of immune checkpoint inhibitors and, when used in combination, to overcome resistance to this group of agents. In addition, ImCheck’s antagonist antibodies are being evaluated as potential treatments for a range of autoimmune diseases.

    Co-founder of the Marseille Immunopole cluster, ImCheck benefits from support from Prof. Daniel Olive (INSERM, CNRS, Institut Paoli Calmettes, Aix-Marseille Université), a worldwide leader in γδ T cells and butyrophilins research; from the experience of an expert management team; and from the commitment of leading US and European investors.

    antibodies, immuno-oncology, Immune checkpoint Modulators, Auto-immunity, innate immunity, oncology, cancer, precision-based medicine, adaptative immunity, EVICTIONtrial, ICT01, and gamma-deltaTcells

  • Original language

    Bringing a novel class of Butyrophilin-targeted checkpoint modulators into the clinic

    ImCheck Therapeutics is designing and developing a new generation of immunotherapeutic antibodies targeting butyrophilins, a novel super-family of immunomodulators.

    As demonstrated by lead clinical-stage program ICT01, which has a mechanism of action to simultaneously modulate innate and adaptive immunity, ImCheck's “first-in-class” activating antibodies may be able to produce superior clinical results as compared to the first-generation of immune checkpoint inhibitors and, when used in combination, to overcome resistance to this group of agents. In addition, ImCheck’s antagonist antibodies are being evaluated as potential treatments for a range of autoimmune diseases.

    Co-founder of the Marseille Immunopole cluster, ImCheck benefits from support from Prof. Daniel Olive (INSERM, CNRS, Institut Paoli Calmettes, Aix-Marseille Université), a worldwide leader in γδ T cells and butyrophilins research; from the experience of an expert management team; and from the commitment of leading US and European investors.

Corporate interactions BETA
Corporate TypeTweets Articles
Chambre de Commerce et d'Industrie Marseille-Provence
Chambre de Commerce et d'Industrie Marseille-Provence
Chamber of commerce, Government Administration
Chambre de Commerce et d'Industrie Marseille-Provence
Chamber of commerce, Government Administration
Other

23 Oct 2024


Direction Générale des Entreprises
Direction Générale des Entreprises
National and local authorities, Government Administration
Direction Générale des Entreprises
National and local authorities, Government Administration
Other

23 Oct 2024


Gustave Roussy
Gustave Roussy
Health, Hospitals and Health Care
Gustave Roussy
Health, Hospitals and Health Care
Other

31 May 2024


Gouvernement Gouvernement
Other

16 Jun 2023


Ministère de la Santé Ministère de la Santé
Other

16 Jun 2023


NEFTYS
NEFTYS
Finance, Financial Services
NEFTYS
Finance, Financial Services
Other

30 May 2024


Ministère de l'Enseignement supérieur et de la Recherche Ministère de l'Enseignement supérieur et de la Recherche
Government Administration
Other

16 Jun 2023


La Coque
La Coque
Events Services
La Coque
Events Services
Other

10 Mar 2023


CNRS Innovation
CNRS Innovation
Research, Research Services
CNRS Innovation
Research, Research Services
Other

21 Feb 2023


La French Tech
La French Tech
Media, Government Administration
La French Tech
Media, Government Administration
Not capitalistic
Not partnership
Event

23 Sep 2023


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