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523 Davis Dr, Morrisville, NC 27560, USA
Morrisville
United States of America
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Scale: 51-200
Estimated: 59
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8Added in Motherbase
5 years, 5 months agoLocus Biosciences, Inc. is a biotechnology company that develops CRISPR-engineered precision antibacterial products.
Next generation CRISPR technology for programmed cell death. Focused on developing therapies for infectious disease and the microbiome.
Locus Biosciences’ novel approach to precision antimicrobials works by taking advantage of a part of an immune system present in many bacteria called the CRISPR-Cas system. The CRISPR-Cas system protects bacteria from invaders such as viruses by creating small strands of RNA called CRISPR RNAs, which match DNA sequences specific to a given invader. When the CRISPR RNAs find a match, they activate Cas proteins that cut the DNA.
Locus Biosciences has developed a platform to design and deliver custom CRISPR-Cas systems directly to specific bacteria. Guided by the custom Locus Bio CRISPRs, the Type-I Cas proteins work to destroy bacterial DNA and cause the bacterial targets to “self-destruct”. Locus’ platform enables the development of antimicrobials which avoid currently known resistance mechanisms while leaving non-target bacteria unharmed. Built on prokaryotic technology for prokaryotic targets, Locus is advancing its platform to create therapeutics for critical-need therapeutic areas ranging from resistant bacterial infections to the microbiome.
CRISPR, Bacterial Infections, Antibiotic Resistance, Biotechnology, Microbiome, and Targeted Therapeutics
AI-enabled Precision Medicine Building engineered bacteriophage therapies for infectious diseases and immunology Learn more about the LOCUS platform Locus
Corporate | Type | Tweets | Articles | |
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Biotechnology Innovation Organization | Other 10 Feb 2024 | | ||
Illumina For Startups Startup accelerator & VC, Biotechnology, Biotechnology Research | Illumina For Startups Startup accelerator & VC, Biotechnology, Biotechnology Research | Other 6 Oct 2016 | | |
GSK Pharmaceutical, Pharmaceutical Manufacturing | GSK Pharmaceutical, Pharmaceutical Manufacturing | Other 19 Nov 2022 | | |
Johnson & Johnson Pharmaceutical, Hospitals and Health Care | Johnson & Johnson Pharmaceutical, Hospitals and Health Care | Not capitalistic Partnership Not event 18 Nov 2021 23 Nov 2022 | | |
General Electric Building supplies, Industrial Machinery Manufacturing | General Electric Building supplies, Industrial Machinery Manufacturing | Other 15 Mar 2016 | | |
Illumina Biotechnology, Biotechnology Research | Illumina Biotechnology, Biotechnology Research | Other 14 Mar 2017 | | |
Novo Nordisk Pharmaceutical, Pharmaceutical Manufacturing | Novo Nordisk Pharmaceutical, Pharmaceutical Manufacturing | Capitalistic Not partnership Not event 19 Nov 2020 | | |
Auvergne-Rhone-Alpes Entreprises - Isère National and local authorities, Business Consulting and Services | Auvergne-Rhone-Alpes Entreprises - Isère National and local authorities, Business Consulting and Services | Not capitalistic Not partnership Event 12 Jan 2021 | |